stress and epigenetics in suicide

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Stress and Epigenetics in Suicide
Author :
Publisher : Academic Press
Release Date :
ISBN 10 : 0128052864
Pages : 236 pages
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Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention. Explores the neurobiology of stress and stress-related epigenetics, including discussion of the role of stress-induced epigenetic changes in behavioral, emotional, and cognitive mechanisms and whether these epigenetic marks are transgenerational Provides compelling biobehavioral models of suicide based on genetics, epigenetics, and behavioral adjustment Integrates social, psychological, and existential influences, giving readers a better understanding of the interdisciplinary nature of suicide risk factors Presents future directions for suicide-prevention strategies that incorporate recent research on genomics and stress resilience

Stress and Epigenetics in Suicide

Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk

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The Neurobiological Basis of Suicide

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention

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The Epigenetics of Suicide

"Suicide is a problem resulting from the interaction between several factors. Among these factors, early-life adversity, characterized by child sexual and physical abuse as well as parental neglect, is one of the strongest risk factors for depression and suicidal behaviors. While it is clear that child abuse increases the risk

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Biological Aspects of Suicidal Behavior

Suicide is one of the most important causes of death in modern societies. To develop more effective preventive measures, we have to be aware of and learn more about its neurobiological foundations. In recent years, the tools of modern neurosciences have increasingly been utilized to characterize the pathophysiology of complex

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Epigenetics in Psychiatry

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances

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Encyclopedia of Psychopharmacology

Here is a broad overview of the central topics and issues in psychopharmacology, biological psychiatry and behavioral neurosciences, with information about developments in the field, including novel drugs and technologies. The more than 2000 entries are written by leading experts in pharmacology and psychiatry and comprise in-depth essays, illustrated with full-color

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The Developing Genome

Why do we grow up to look, act, and feel as we do? Through most of the twentieth century, scientists and laypeople answered this question by referring to two factors alone: our experiences and our genes. But recent discoveries about how genes work have revealed a new way to understand

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Epigenetics of Stress and Stress Disorders

As the known influence of epigenetic responses to pathological stress and stress related disorders increases, so does our understanding of why individuals possess different levels of resilience after experiencing the same trauma. Epigenetics of Stress and Stress Related Disorders, a new volume in the Translational Epigenetics Series, examines the epigenetic

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Environmental Epigenetics

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks

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DNA Methylation  and the Stress Response in the Anterior Cingulate Cortex of Abused Suicide Completers

"Suicide is a major health problem in Canada and around the globe. Studies have shown that individuals with a history of childhood abuse are more likely to commit suicide and neurobiological correlates have been identified in these individuals. Some of these biological changes have included over-activity of stress response pathways

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Restriction Landmark Genomic Scanning  RLGS

Restriction Landmark Genomic Scanning (RLGS) is a new multiplex method for simultaneous analysis of over 3,000 genome loci. Written by the inventor of RLGS, Yoshihide Hayashizaki, and his co-workers, this is the first manual on this method. RLGS is a powerful technique with enormous potential for biological (animal and plant sciences),

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Alternatives to Suicide

Alternatives to Suicide: Beyond Risk and Toward a Life Worth Living demonstrates how fostering resilience and a desire for life can broaden and advance an understanding of suicide. The book summarizes the existing literature and outlines a new focus on the dynamic interplay of risk and resilience that leads to

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Stress  Concepts  Cognition  Emotion  and Behavior

Stress: Concepts, Cognition, Emotion, and Behavior: Handbook in Stress Series, Volume 1, examines stress and its management in the workplace and is targeted at scientific and clinical researchers in biomedicine, psychology, and some aspects of the social sciences. The audience is appropriate faculty and graduate and undergraduate students interested in stress

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International Handbook of Suicide Prevention

The International Handbook of Suicide Prevention showcases the latest cutting-edge research from the world’s leading authorities, and highlights policy and practice implications for the prevention of suicide. Brings together the world’s leading authorities on suicidal behaviour, renowned for their suicide prevention research, policy and practice Addresses the key

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Phenomenology of Suicide

This book will help the reader to understand the suicidal mind from a phenomenological point of view, shedding light on the feelings of suicidal individuals and also those of clinicians. In accordance with the importance that the phenomenological approach attaches to subjectivity and sense of self as the starting points

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