phenotypic switching

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Phenotypic Switching
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Publisher : Academic Press
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ISBN 10 : 012817997X
Pages : 762 pages
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Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast. Thoroughly addresses the conceptual, experimental and translational aspects that underlie phenotypic plasticity Emphasizes quantitative approaches, nonlinear dynamics, mechanistic insights and key methodologies to advance phenotypic plasticity studies Features a diverse range of chapter contributions from international leaders in the field

Phenotypic Switching

Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications

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A Mechanistic and Functional Study of White opaque Phenotypic Switching in Candida Albicans

Candida albicans is a major fungal pathogen of humans. It is a harmless commensal in healthy individuals, but it can cause serious infections in immune-compromised hosts. C. albicans undergoes a meta-stable and reversible switch between two distinct cell types known as white and opaque. The role of white-opaque switching in

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Candida Albicans Phenotypic Switching and Functional Plasticity in the Mammalian Host

In order to determine the host signals and fungal signaling pathways that control the white-GUT switch and drive commensalism, we developed an in vitro system to induce switching behavior and screened a library of C. albicans signaling mutants. We identified three fungal signaling pathways (Hog1, Rim101, and PKA), previously associated

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Interactions Between Phenotypic Switching  Gene Network Dynamics and Evolutionary Dynamics in Growing Cell Populations

Gene expression is a stochastic biological processes that controls the different phenotypes of an organism depending on the environment. High-resolution single cell measurements show that genetically identical cells can be different from each other even in a homogeneous environment, leading a spectrum of phenotypes with different cellular fitnesses that can

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Proceedings of the National Academy of Sciences of the United States of America

Download or read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by Unknown which was released on 2007. Get Proceedings of the National Academy of Sciences of the United States of America Books now! Available in

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Molecular Biology of Fungal Development

This text gives an overview of the fundamental aspects of molecular fungal development in one comprehensive volume, highlighting different elements in the maturational and reproductive cycles of selected fungal taxa.

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Microbiology

Download or read online Microbiology written by Anonim, published by Unknown which was released on 1997. Get Microbiology Books now! Available in PDF, ePub and Kindle.

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Archives of Medical Research

Download or read online Archives of Medical Research written by Anonim, published by Unknown which was released on 1993. Get Archives of Medical Research Books now! Available in PDF, ePub and Kindle.

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Cellular and Phenotypic Plasticity in Cancer

The process of Epithelial-Mesenchymal-Transition (EMT) is known to result in a phenotype change in cells from a proliferative state to a more invasive state. EMT has been reported to drive the metastatic spread of various cancers and has also been associated with drug resistance to cytotoxics and targeted therapeutics. Recently

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Clinical Mycology

The first textbook of mycology ever to focus on the management of patients with fungal infections, CLINICAL MYCOLOGY represents an expert, authoritative examination of clinical problem-solving approaches to diagnosis and management. It offers specific recommendations for understanding, controlling, and preventing fungal infections based on underlying principles of epidemiology and infection

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Oral Manifestations of HIV Infection

Brings together the papers presented at this important 1993 workshop. Addressed is a wide array of issues of interest to the dental practitioner and researcher, from oral lesions to periodontal concerns to provision of care and infection control practices. [editor].

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Postnaupliar Development of a Looking glass

Download or read online Postnaupliar Development of a Looking glass written by Frank D. Ferrari, published by Unknown which was released on 1985. Get Postnaupliar Development of a Looking glass Books now! Available in PDF, ePub and Kindle.

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Smithsonian Contributions to Zoology

Download or read online Smithsonian Contributions to Zoology written by Anonim, published by Unknown which was released on 1969. Get Smithsonian Contributions to Zoology Books now! Available in PDF, ePub and Kindle.

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Microbial Determinants of Virulence and Host Response

Proceedings of a workshop held at the U. of Florida Health Center in Gainesville, February 1989. Surveys and evaluates the status of research in the related fields of bacteriology, mycology, immunology, and host-parasite relationships. The five sections address bacterial factors; fungal factors; bacterial factors in sexually transmitted diseases; biologic factors; and

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Journal of Recent Advances in Applied Sciences

Download or read online Journal of Recent Advances in Applied Sciences written by Anonim, published by Unknown which was released on 1997. Get Journal of Recent Advances in Applied Sciences Books now! Available in PDF, ePub and Kindle.

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