phenotypic switching

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Phenotypic Switching
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Publisher : Academic Press
Release Date :
ISBN 10 : 012817997X
Pages : 762 pages
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Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications in cancer therapy, regenerative medicine and stem cell therapy, among other treatments. Chapters discuss fundamental mechanisms of phenotypic switching, including transition states, cell fate decisions, epigenetic factors, stochasticity, protein-based inheritance, specific areas of human development and disease relevance, phenotypic plasticity in melanoma, prostate cancer, breast cancer, non-genetic heterogeneity in cancer, hepatitis C, and more. This book is essential for active researchers, basic and translational scientists, clinicians, postgraduates and students in genetics, human genomics, pathology, bioinformatics, developmental biology, evolutionary biology and adaptive opportunities in yeast. Thoroughly addresses the conceptual, experimental and translational aspects that underlie phenotypic plasticity Emphasizes quantitative approaches, nonlinear dynamics, mechanistic insights and key methodologies to advance phenotypic plasticity studies Features a diverse range of chapter contributions from international leaders in the field

Phenotypic Switching

Phenotypic Switching: Implications in Biology and Medicine provides a comprehensive examination of phenotypic switching across biological systems, including underlying mechanisms, evolutionary significance, and its role in biomedical science. Contributions from international leaders discuss conceptual and theoretical aspects of phenotypic plasticity, its influence over biological development, differentiation, biodiversity, and potential applications

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A Mechanistic and Functional Study of White opaque Phenotypic Switching in Candida Albicans

Candida albicans is a major fungal pathogen of humans. It is a harmless commensal in healthy individuals, but it can cause serious infections in immune-compromised hosts. C. albicans undergoes a meta-stable and reversible switch between two distinct cell types known as white and opaque. The role of white-opaque switching in

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Phenotypic Switching in Bacteria

Download or read online Phenotypic Switching in Bacteria written by Jack Merrin, published by Unknown which was released on 2006. Get Phenotypic Switching in Bacteria Books now! Available in PDF, ePub and Kindle.

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Phenotypic Switching in Candida Albicans

Download or read online Phenotypic Switching in Candida Albicans written by Vaneesha Stewart Gibbons, published by Unknown which was released on 1999. Get Phenotypic Switching in Candida Albicans Books now! Available in PDF, ePub and Kindle.

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Phenotypic Switching and Mating in the Pathogenic Yeast Candida Albicans

Download or read online Phenotypic Switching and Mating in the Pathogenic Yeast Candida Albicans written by Rui Zhao, published by Unknown which was released on 2004. Get Phenotypic Switching and Mating in the Pathogenic Yeast Candida Albicans Books now! Available in PDF, ePub and Kindle.

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HOS3 Function in Phenotypic Switching of Candida Albicans

Download or read online HOS3 Function in Phenotypic Switching of Candida Albicans written by Yong You, published by Unknown which was released on 2002. Get HOS3 Function in Phenotypic Switching of Candida Albicans Books now! Available in PDF, ePub and Kindle.

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Phenotypic Switching of Bacterial Cells in Extreme Environments

A large number of terrestrial microbial lives thrive in extremes of environmental conditions, including extremes of pressure, temperature, salinity, pH, and a combination of them. For example, all the marine biomass thrive at high hydrostatic pressure depending on depth. The temperature in the ocean can be very high near the

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Cloning and Characterization of Two Genes Regulated with Phenotypic Switching in the Pathogenic Yeast Candida Albicans

Download or read online Cloning and Characterization of Two Genes Regulated with Phenotypic Switching in the Pathogenic Yeast Candida Albicans written by Brian James Morrow, published by Unknown which was released on 1994. Get Cloning and Characterization of Two Genes Regulated with Phenotypic Switching in the Pathogenic Yeast Candida Albicans Books

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Interactions Between Phenotypic Switching  Gene Network Dynamics and Evolutionary Dynamics in Growing Cell Populations

Gene expression is a stochastic biological processes that controls the different phenotypes of an organism depending on the environment. High-resolution single cell measurements show that genetically identical cells can be different from each other even in a homogeneous environment, leading a spectrum of phenotypes with different cellular fitnesses that can

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The Role of Phenotypic Switching in the Pathogenicity of Oral Candida Albicans in the Immunosuppressed Bone Marrow Transplantation Patient

Download or read online The Role of Phenotypic Switching in the Pathogenicity of Oral Candida Albicans in the Immunosuppressed Bone Marrow Transplantation Patient written by Kelly John Wright, published by Unknown which was released on 1993. Get The Role of Phenotypic Switching in the Pathogenicity of Oral Candida Albicans in the

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Identification of Genetic Elements Involved in Regulating Phenotypic Switching in Pseudomonas Tolaasii

Download or read online Identification of Genetic Elements Involved in Regulating Phenotypic Switching in Pseudomonas Tolaasii written by Cara Patricia Owens, published by Unknown which was released on 2005. Get Identification of Genetic Elements Involved in Regulating Phenotypic Switching in Pseudomonas Tolaasii Books now! Available in PDF, ePub and Kindle.

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Candida Albicans Phenotypic Switching and Functional Plasticity in the Mammalian Host

In order to determine the host signals and fungal signaling pathways that control the white-GUT switch and drive commensalism, we developed an in vitro system to induce switching behavior and screened a library of C. albicans signaling mutants. We identified three fungal signaling pathways (Hog1, Rim101, and PKA), previously associated

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A New Insertion Sequence Ist1 and Its Association with Phenotypic Switching in Thiobacillus Ferrooxidans

Download or read online A New Insertion Sequence Ist1 and Its Association with Phenotypic Switching in Thiobacillus Ferrooxidans written by Huiling Zhao, published by Unknown which was released on 1994. Get A New Insertion Sequence Ist1 and Its Association with Phenotypic Switching in Thiobacillus Ferrooxidans Books now! Available in PDF, ePub

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Regulation of Phenotypic Switching and Heterogeneity in Photorhabdus Luminescens Cell Populations

Download or read online Regulation of Phenotypic Switching and Heterogeneity in Photorhabdus Luminescens Cell Populations written by Angela Katharina Langer, published by Unknown which was released on 2016. Get Regulation of Phenotypic Switching and Heterogeneity in Photorhabdus Luminescens Cell Populations Books now! Available in PDF, ePub and Kindle.

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Cellular and Phenotypic Plasticity in Cancer

The process of Epithelial-Mesenchymal-Transition (EMT) is known to result in a phenotype change in cells from a proliferative state to a more invasive state. EMT has been reported to drive the metastatic spread of various cancers and has also been associated with drug resistance to cytotoxics and targeted therapeutics. Recently

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