natural hosts of siv

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Natural Hosts of SIV
Author :
Publisher : Newnes
Release Date :
ISBN 10 : 0124051677
Pages : 400 pages
Rating : /5 ( users)
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Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to treat and prevent HIV. When Asian non-human primate non-natural hosts are experimentally infected with viruses isolated from African species, disease and death normally results. Meanwhile, these African nonhuman primate natural hosts maintain similar levels of plasma and cellular viremia and exhibit compellingly different, essentially disease-free, states. This work attempts to answer the question of how the natural host remains disease resistant. Summarizes the past 30 years of research in this field and describes the latest developments in AIDS research using nonhuman primate animal models Provides insights into how this large body of scientific work can be translated into novel approaches to treat and prevent HIV Highlights the areas that merit future pursuit, focusing on potential applications for the treatment and prevention of HIV infection

Natural Hosts of SIV

Natural Hosts of SIV: Implications in AIDS thoroughly reviews the possible mechanisms by which African nonhuman primate natural hosts of lentiviruses remain essentially disease-free while other hosts exhibit disease and death. The book ultimately indicates directions for further research and potential translations of this compelling phenomenon into novel approaches to

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AIDS Pathogenesis

Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as

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Experimentally induced Immune Activation in Natural Hosts of SIV Induces Significant Increases in Viral Replication and CD4  T Cell Depletion

Chronically SIVagm-infected African green monkeys (AGMs) have a remarkably stable non-pathogenic disease course, with levels of immune activation in chronic SIVagm infection similar to those observed in uninfected monkeys and stable viral loads (VLs) for long periods of time. In vivo administration of lipopolysaccharide (LPS) or an IL-2/diphtheria toxin

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The Evolution of HIV

"As a model for viral evolution, this book is a gold mine." -- European Molecular Biology Organization Reports

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Distinct Patterns of CCR5 Versus Alternative Coreceptor Dependence in Non natural Host Versus Natural Host Simmian Immunodeficiency Virus Infection

Natural host sooty mangabeys infected with simian immunodeficiency viruses (SIV) exhibit high plasma viral loads without widespread CD4+ T cell loss. By contrast, non-natural host rhesus macaques experimentally infected with related SIV exhibit high viral loads but display subsequent CD4+ T cell loss and progression to AIDS, analogous to the

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Viral Sex

Leading AIDS researcher Jaap Goudsmit illuminates the origins and nature of the world's most lethal epidemic. Goudsmit takes us on a journey from the African rainforest to ancient Egypt to pioneering research labs in the U.S. and Europe. Impeccably researched, VIRAL SEX instills readers with a new sense of

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Encyclopedia of AIDS

For the first time, the world’s experts in HIV-AIDS have come together to publish the Encyclopedia of AIDS. The work features over 4000 A-Z entries including medical, cultural, social, and pharmacological essays. The Pathology entries cover the various types of HIV-related illnesses, including those that are and are not AIDS-defining.

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Parasite Diversity and Diversification

By joining phylogenetics and evolutionary ecology, this book explores the patterns of parasite diversity while revealing diversification processes.

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Spillover  Animal Infections and the Next Human Pandemic

"[Mr. Quammen] is not just among our best science writers but among our best writers, period." —Dwight Garner, New York Times The next big human pandemic—the next disease cataclysm, perhaps on the scale of AIDS or the 1918 influenza—is likely to be caused by a new virus coming to

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Models of Protection Against HIV SIV

A successful vaccine for the prevention and/or immunotherapy against HIV/AIDS is one of the prominent challenges of the 21st century. To date, all human vaccine trials against this virus/disease have resulted in failure, or at best have shown very low efficacy. The scientific community dealing with HIV/

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The Chimp and the River  How AIDS Emerged from an African Forest

In this "frightening and fascinating masterpiece" (Walter Isaacson), David Quammen explores the true origins of HIV/AIDS. The real story of AIDS—how it originated with a virus in a chimpanzee, jumped to one human, and then infected more than 60 million people—is very different from what most of us

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Vesicular Diseases

Download or read online Vesicular Diseases written by Anonim, published by Unknown which was released on 1997. Get Vesicular Diseases Books now! Available in PDF, ePub and Kindle.

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Foamy Viruses

The aberrant replication pathway of foamy viruses distinguishes them from all other retroviruses. Many details have been accumulated over the past ten or so years. Most of the findings on foamy viruses were obtained by research on a single virus isolate previously called "human foamy virus", which appeared to be

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The Origins of AIDS

An updated edition of Jacques Pépin's acclaimed account of the events that transformed a chimpanzee virus into a global pandemic.

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Occupational Health and Safety in the Care and Use of Nonhuman Primates

The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed,

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