laboratory exercises in molecular pathology

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Laboratory Exercises in Molecular Pathology
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Publisher : Academic Press
Release Date :
ISBN 10 : 9780128006085
Pages : 400 pages
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Laboratory Exercises in Molecular Pathology is organized by major organ systems and then by disease type. In each exercise, there is a distillation of essential disease-specific information (related to frequency, risk factors, disease manifestations) and a description of disease pathogenesis (molecular and cellular) that is based upon accepted principles from the literature. Further, each exercise is illustrated with (1) gross specimens, (2) microscopic histopathology, (3) immunohistochemistry and/or in situ hybridization (when applicable), (4) laboratory techniques to probe the molecular nature of the pathological lesions, and (5) molecular diagnostics (when applicable). In addition, each exercise contains one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment. The laboratory techniques included emphasize the dissection of molecular and cellular pathogenesis of the disease in question. Hence, students will see examples of laboratory results that illustrate how pathways were elucidated. Further, the sections on molecular diagnostics illustrate how molecular testing exploits what is known about molecular pathogenesis in a specific disease setting. The manual does not present molecular methods and techniques in isolation; it illustrates how these experimental approaches and applied methodologies can be used to generate meaningful information in the clinical setting. Presents foundational information, examples of gross and microscopic pathology, and examples of molecular approaches and molecular testing all in one resource Offers an ancillary website with videos corresponding to the evaluation of gross specimens, the assessment of microscopic images, and the demonstration of how laboratory techniques are performed Features exercises which contain one or more cases studies to provide students with exposure to the clinical workup of a patient, based upon physical examination findings, traditional pathological analysis, and state-of-the-art molecular assessment Provides case studies which include self-assessment modules and decision trees that allow students to make mistakes and then receive explanations

Laboratory Exercises in Molecular Pathology

Laboratory Exercises in Molecular Pathology is organized by major organ systems and then by disease type. In each exercise, there is a distillation of essential disease-specific information (related to frequency, risk factors, disease manifestations) and a description of disease pathogenesis (molecular and cellular) that is based upon accepted principles from

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