epigenetic mechanisms in the brain

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Epigenetic Mechanisms in Neural Plasticity
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Publisher : Frontiers Media SA
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ISBN 10 : 2889630005
Pages : null pages
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Neural plasticity is a unique and adaptive feature of nervous system, which allows neurons to reorganize their interactions in response to a stimulation (intrinsic or extrinsic) to maintain their function. For these reasons, epigenetics emerges as a potential field for developing strategies to modulate changes in pathological situation because extrinsic factors and pharmacological tools can modify neural functioning in organisms during their life. Diet, exercise, environmental aspects, stressors or drugs are available to alter those mechanisms. Epigenetic involves certain molecular signaling pathways, as DNA methylation and histone acetylation and deacetylation, and the emerging non-coding small RNA, mainly microRNA, as a commanders of a number of translation processes. As most of molecular nervous cell alterations, epigenetic mechanisms play an important role in neural plasticity. This eBook collects the burgeoning advances in epigenetic mechanisms, focusing on new insights into cellular and molecular neurobiological mechanisms that underlie brain functioning in health and pathological conditions. Contributions go from basic cellular mechanism to therapeutic opportunities to tackle the challenges on nervous central system development and neurodegeneration.

Epigenetic Mechanisms in Neural Plasticity

Neural plasticity is a unique and adaptive feature of nervous system, which allows neurons to reorganize their interactions in response to a stimulation (intrinsic or extrinsic) to maintain their function. For these reasons, epigenetics emerges as a potential field for developing strategies to modulate changes in pathological situation because extrinsic

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Genetic and Epigenetic Mechanisms in Down Syndrome Brain

Genetic and Epigenetic Mechanisms in Down Syndrome Brain.

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Epigenetic Regulation in the Nervous System

Epigenetic Regulation in the Nervous System addresses current understanding of the roles of epigenetic processes at the molecular/cellular level, their impact on neural development and behavior, and the potential roles of these mechanisms in neurological and psychiatric disorders. This award-winning volume spans molecular epigenetics, development, cellular physiology and biochemistry,

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Epigenetic Mechanisms in the Brain

Epigenetic Mechanisms in the Brain provides recent findings in the field of neuroepigenetics, covering how our genes encode our memories, transmit information about stressful events, and play a part in our addictions. This book helps to unlock these abstract processes, with a forward goal of improving individualized treatments. Discusses how

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The Neurobiological Basis of Suicide

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention

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Epigenetics  Brain and Behavior

What lies at the heart of neuronal plasticity? Accumulating evidence points to epigenetics. This word originally indicated potentially heritable modifications in gene expression that do not involve changes in DNA sequence. Today this definition is much less strict, and epigenetic control is thought to include DNA methylation, histone modifications, histone

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Epigenetics and Neuroplasticity   Evidence and Debate

The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—including DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the

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Epigenetic Regulation in the Nervous System

Download or read online Epigenetic Regulation in the Nervous System written by Jeremy J. Day,J. David Sweatt, published by Elsevier Inc. Chapters which was released on 2012-12-31. Get Epigenetic Regulation in the Nervous System Books now! Available in PDF, ePub and Kindle.

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Surveillance for Traumatic Brain Injury related Deaths

Traumatic brain injury (TBI) is a leading cause of death and disability in the United States. Approximately 53,000 persons die from TBI-related injuries annually. During 1989–1998, TBI-related death rates decreased 11.4%, from 21.9 to 19.4 per 100,000 population. This report describes the epidemiology and annual rates of TBI-related deaths during 1997–2007.

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Epigenetics in Psychiatry

Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances

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Epigenetic Information processing Mechanisms in the Brain

Download or read online Epigenetic Information processing Mechanisms in the Brain written by Lawrence R. Edelstein,John Raymond Smythies,Denis Noble, published by Unknown which was released on 2014. Get Epigenetic Information processing Mechanisms in the Brain Books now! Available in PDF, ePub and Kindle.

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Behavioral Neurogenomics

This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms

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Epigenetics and Metabolomics

Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic

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Epigenetic Mechanisms and Their Involvement in Rare Diseases

Download or read online Epigenetic Mechanisms and Their Involvement in Rare Diseases written by Mojgan Rastegar,Dag H. Yasui, published by Frontiers Media SA which was released on 2021-10-20. Get Epigenetic Mechanisms and Their Involvement in Rare Diseases Books now! Available in PDF, ePub and Kindle.

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Handbook of Epigenetics

Handbook of Epigenetics: The New Molecular and Medical Genetics, Second Edition, provides a comprehensive analysis of epigenetics, from basic biology, to clinical application. Epigenetics is considered by many to be the new genetics in that many biological phenomena are controlled, not through gene mutations, but rather through reversible and heritable

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