epigenetic biomarkers and diagnostics

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Epigenetic Biomarkers and Diagnostics
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Publisher : Academic Press
Release Date :
ISBN 10 : 0128019212
Pages : 696 pages
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Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based technologies to discover and analyze epigenetic biomarkers. The book concludes with an account of DNA methylation, post-translational modifications and noncoding RNAs as the most promising biomarkers for cancer (i.e. breast, lung, colon, etc.), metabolic disorders (i.e. diabetes and obesity), autoimmune diseases, infertility, allergy, infectious diseases, and neurological disorders. The book describes the challenging aspects of research in epigenetics, and current findings regarding new epigenetic elements and modifiers, providing guidance for researchers interested in the most advanced technologies and tested biomarkers to be used in the clinical diagnosis or prognosis of disease. Focuses on recent progress in several areas of epigenetics, general concepts regarding epigenetics, and the future prospects of this discipline in clinical diagnostics and prognostics Describes the importance of the quality of samples and clinical associated data, and also the ethical issues for epigenetic diagnostics Discusses the advances in epigenomics technologies, including next-generation sequencing based tools and applications Expounds on the utility of epigenetic biomarkers for diagnosis and prognosis of several diseases, highlighting the study of these biomarkers in cancer, cardiovascular and metabolic diseases, infertility, and infectious diseases Includes a special section that discusses the relevance of biobanks in the maintenance of high quality biosamples and clinical-associated data, and the relevance of the ethical aspects in epigenetic studies

Epigenetic Biomarkers and Diagnostics

Epigenetic Biomarkers and Diagnostics comprises 31 chapters contributed by leading active researchers in basic and clinical epigenetics. The book begins with the basis of epigenetic mechanisms and descriptions of epigenetic biomarkers that can be used in clinical diagnostics and prognostics. It goes on to discuss classical methods and next generation sequencing-based

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Prognostic Epigenetics

This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for

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Nucleic Acids based Molecular Diagnostics in Genetic and Epigenetic Biomarkers

Download or read online Nucleic Acids based Molecular Diagnostics in Genetic and Epigenetic Biomarkers written by Zhuo Zhang, published by Unknown which was released on 2019. Get Nucleic Acids based Molecular Diagnostics in Genetic and Epigenetic Biomarkers Books now! Available in PDF, ePub and Kindle.

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DNA Methylation and Complex Human Disease

DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as

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Epigenetic Mechanisms in Cancer

Epigenetic Mechanisms in Cancer provides a comprehensive analysis of epigenetic signatures that govern disease development, progression and metastasis. Epigenetic signatures dictating tumor etiologies present an opportunity for biomarker identification which has broad potential for improving diagnosis, prognosis, prediction, and risk assessment. This volumes offers a unique evaluation of signature differences

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Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of Wif1 Functional Relevance

This dissertation, "Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of WIF1 Functional Relevance" by Xuesong, Yang, 楊雪松, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not

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Epigenetics in Precision Medicine

In recent years, knowledge of epigenetic mechanisms underlying disease onset and progression has proven crucial for the development of novel early diagnosis and prognosis biomarkers for patient stratification and precision medicine. Epigenetics in Precision Medicine, a new volume in the Translational Epigenetics series, provides a thorough discussion and overview of

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Epigenetic Biomarker and Personalized Precision Medicine

Download or read online Epigenetic Biomarker and Personalized Precision Medicine written by Jiucun Wang,Dongyi He,Momiao Xiong,Yun Liu, published by Frontiers Media SA which was released on 2020-12-21. Get Epigenetic Biomarker and Personalized Precision Medicine Books now! Available in PDF, ePub and Kindle.

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Drug Discovery in Cancer Epigenetics

Drug Discovery in Cancer Epigenetics is a practical resource for scientists involved in the discovery, testing, and development of epigenetic cancer drugs. Epigenetic modifications can have significant implications for translational science as biomarkers for diagnosis, prognosis or therapy prediction. Most importantly, epigenetic modifications are reversible and epigenetic players are found

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Novel Epigenetic Biomarkers for Diagnosis  Prognosis and Response Prediction in Colorectal Cancer

Download or read online Novel Epigenetic Biomarkers for Diagnosis Prognosis and Response Prediction in Colorectal Cancer written by Marc Tänzer, published by Unknown which was released on 2012. Get Novel Epigenetic Biomarkers for Diagnosis Prognosis and Response Prediction in Colorectal Cancer Books now! Available in PDF, ePub and Kindle.

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Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of WIF1 Functional Relevance

Download or read online Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of WIF1 Functional Relevance written by Anonim, published by Unknown which was released on 2014. Get Identification of Epigenetic Biomarkers for Diagnosis of Nasopharyngeal Carcinoma and Determination of WIF1 Functional Relevance Books now! Available in PDF,

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Cancer and Noncoding RNAs

Cancer and Noncoding RNAs offers an in-depth exploration of noncoding RNAs and their role in epigenetic regulation of complex human disease, most notably cancer. In addition to examining microRNAs, this volume provides a unique evaluation of more recently profiled noncoding RNAs now implicated in carcinogenesis, including lncRNAs, piRNAs, circRNAs, and

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Computational Epigenetics and Diseases

Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized,

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Clinical Epigenetics

In genetic pathology, epigenetic testing is rare and under utilised. In this book, we introduce epigenetics to a non-expert scientific audience and describe current and future clinical utility of epigenetic testing. By focussing on epigenetics in human disease this book will guide professionals (scientists and clinicians) to understand how epigenetics

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Epigenetic Cancer Therapy

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the

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