cytogenomics

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Cytogenomics
Author :
Publisher : Academic Press
Release Date :
ISBN 10 : 0128235802
Pages : 428 pages
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Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods and technologies, enabling researchers to jump-start their own projects and more effectively gather and interpret chromosomal data. Methods discussed include banding and molecular cytogenetics, molecular combing, molecular karyotyping, next-generation sequencing, epigenetic study approaches, optical mapping/karyomapping, and CRISPR-cas9 applications for cytogenomics. The book’s second half demonstrates recent applications of cytogenomic techniques, such as characterizing 3D chromosome structure across different tissue types and insights into multilayer organization of chromosomes, role of repetitive elements and noncoding RNAs in human genome, studies in topologically associated domains, interchromosomal interactions, and chromoanagenesis. This book is an important reference source for researchers, students, basic and translational scientists, and clinicians in the areas of human genetics, genomics, reproductive medicine, gynecology, obstetrics, internal medicine, oncology, bioinformatics, medical genetics, and prenatal testing, as well as genetic counselors, clinical laboratory geneticists, bioethicists, and fertility specialists. Offers applied approaches empowering a new generation of cytogenomic research using a balanced combination of classical and advanced technologies Provides a framework for interpreting chromosome structure and how this affects the functioning of the genome in health and disease Features chapter contributions from international leaders in the field

Cytogenomics

Cytogenomics demonstrates that chromosomes are crucial in understanding the human genome and that new high-throughput approaches are central to advancing cytogenetics in the 21st century. After an introduction to (molecular) cytogenetics, being the basic of all cytogenomic research, this book highlights the strengths and newfound advantages of cytogenomic research methods

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The AGT Cytogenetics Laboratory Manual

Cytogenetics is the study of chromosome morphology, structure, pathology, function, and behavior. The field has evolved to embrace molecular cytogenetic changes, now termed cytogenomics. Cytogeneticists utilize an assortment of procedures to investigate the full complement of chromosomes and/or a targeted region within a specific chromosome in metaphase or interphase.

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Comparative Cytology and Cytogenomics for Representative Species of the Five Duckweed Genera

Cytogenetic; chromosome rearrangement; chromosome homeology; duckweed; Fluorescence In situ hybridization (FISH); guard cell; genome size

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Cytogenomics of Human Oocytes and Embryos

Download or read online Cytogenomics of Human Oocytes and Embryos written by Alem Selassie Gabriel, published by Unknown which was released on 2011. Get Cytogenomics of Human Oocytes and Embryos Books now! Available in PDF, ePub and Kindle.

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Iscn 2020

This reprint of 'Cytogenetic and Genome Research' contains contributions discussing the subject in-depth. 'Cytogenetic and Genome Research' is a well-respected, international peer-reviewed journal in genetics.

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Comparative Cytogenomics Between Chicken and Duck

Download or read online Comparative Cytogenomics Between Chicken and Duck written by Benjamin Matthew Skinner, published by Unknown which was released on 2009. Get Comparative Cytogenomics Between Chicken and Duck Books now! Available in PDF, ePub and Kindle.

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Human Interphase Chromosomes

This title will focus on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and human genome function in interphase nuclei at the chromosomal level have been repeatedly shown to play a significant role in a variety of basic biological processes involved in realization

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Cytogenetics

Cytogenetics - Past, Present, and Further Perspectives discusses events that influenced the development of cytogenetics as a specialty within biology, with special attention paid to methodological achievements developed worldwide that have driven the field forward. Improvements to the resolution of chromosome analysis followed closely the introduction of innovative analytical technologies.

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Iscn 2016

The 2016 edition of the International System for Human Cytogenomic Nomenclature (ISCN 2016) offers standard nomenclature that is used to describe any genomic rearrangement identified by techniques ranging from karyotyping to FISH, microarray, various region specific assays, and DNA sequencing. Suggestions from the international cytogenetics community have been reviewed by the Standing

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Genetics  Evolution  and Conservation of Neotropical Fishes

Fish represent the most ancestral and specious group of vertebrates, and occupy more diverse aquatic environments around the world. Ichthyofauna is extremely diverse, especially in megadiverse countries occupying biogeographical regions such as the Neotropical Region, which covers an extensive area between North and South America. Much of this biodiversity will

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Molecular Diagnostics

Molecular Diagnostics, Third Edition, focuses on the technologies and applications that professionals need to work in, develop, and manage a clinical diagnostic laboratory. Each chapter contains an expert introduction to each subject that is next to technical details and many applications for molecular genetic testing that can be found in

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Cytogenetic Laboratory Management

Cytogenetic Laboratory Management: Chromosomal, FISH and Microarray-Based Best Practices and Procedures is a practical guide that describes how to develop and implement best practice processes and procedures in the genetic laboratory setting. The text first describes good laboratory practices, including quality management, design control of tests and FDA guidelines for

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Clinical Genomics

Clinical Genomics provides an overview of the various next-generation sequencing (NGS) technologies that are currently used in clinical diagnostic laboratories. It presents key bioinformatic challenges and the solutions that must be addressed by clinical genomicists and genomic pathologists, such as specific pipelines for identification of the full range of variants

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Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber  Cucumis Sativus L   Mitochondrial Genome

Download or read online Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber Cucumis Sativus L Mitochondrial Genome written by Jason Warren Lilly, published by Unknown which was released on 2000. Get Investigations Into the Organellar Genomes of Higher Plants with a Focus on the Cucumber

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Pharmacogenomics

Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book

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