cell polarity in development and disease

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Cell Polarity in Development and Disease
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Publisher : Academic Press
Release Date :
ISBN 10 : 0128125918
Pages : 236 pages
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Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of cell polarity in the onset and progression of cancer. This book provides a basic resource for understanding the biology of polarity, offering a starting point for those thinking of targeting cell polarity for translational medical research. Provides basic science understanding of cell polarity disease and development Covers diseases affecting polarized epithelial tissues in the lung and kidney, also covering the progression of cancer Includes historical context of cell polarity research for potential future breakthroughs

Cell Polarity in Development and Disease

Cell Polarity in Development and Disease offers insights into the basic molecular mechanisms of common diseases that arise as a result of a loss of ordered organization and intrinsic polarity. Included are diseases affecting highly polarized epithelial tissues in the lung and kidney, as well as loss and gain of

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The Role of Cell polarity in Development and Disease

Download or read online The Role of Cell polarity in Development and Disease written by Payman Samavarchi-Tehrani, published by Unknown which was released on 2013. Get The Role of Cell polarity in Development and Disease Books now! Available in PDF, ePub and Kindle.

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Cell Polarity 2

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 2 discusses the physiological and pathophysiological relevance of cell polarity. It especially focuses on pathophysiological conditions in which one or several aspects of cell polarity are impaired, and in which a loss of cell polarity

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Planar Cell Polarity in Kidney Development and Disease

Download or read online Planar Cell Polarity in Kidney Development and Disease written by Hortensja Łucja Brzóska, published by Unknown which was released on 2017. Get Planar Cell Polarity in Kidney Development and Disease Books now! Available in PDF, ePub and Kindle.

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Planar Cell Polarity in Kidney Development and Disease

Download or read online Planar Cell Polarity in Kidney Development and Disease written by H. L. Brzoska, published by Unknown which was released on 2017. Get Planar Cell Polarity in Kidney Development and Disease Books now! Available in PDF, ePub and Kindle.

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Cellular Adhesion in Development and Disease

Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and

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Adherens Junctions  from Molecular Mechanisms to Tissue Development and Disease

Cell–cell adhesion is fundamental for the development and homeostasis of animal tissues and organs. Adherens junctions (AJs) are the best understood cell-cell adhesion complexes. In this volume, a group of internationally recognized experts reviews AJ biology over a wide range of organization; from atoms to molecules, to protein complexes,

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Cell Polarity

Most animal cells are polarized, with structurally and functionally distinct regions. This polarization facilitates processes such as differentiation and morphogenesis, directional cell migration, nerve impulse transmission, and transport of molecules across tissues. The dysregulation of these processes can lead to developmental disorders and is a feature of many cancers. Written

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Role of Planar Cell Polarity Gene Vangl2 in Kidney Development and Disease

"The Planar Cell Polarity (PCP) signaling pathway is crucial for tissue morphogenesis. Vangl2 protein is central in the PCP pathway: its loss is embryonic lethal causing neural tube defects in mice and humans. In the kidney, PCP signaling is thought to be important for the organization of glomerular epithelial cells,

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Methods in Kidney Cell Biology Part B

Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary

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Planar Cell Polarity

Planar cell polarity (PCP), or the alignment of a collection of cells within a cell sheet, has proven, over time, to be vital in not only normal development but also in disease states. In Planar Cell Polarity: Methods and Protocols, expert researchers in the field present a number of detailed

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Cell Polarity 1

This work provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It

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GTPases Regulating Membrane Dynamics

Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.

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Shaping the Brain by Neuronal Cytoskeleton  from Development to Disease and Regeneration

Download or read online Shaping the Brain by Neuronal Cytoskeleton from Development to Disease and Regeneration written by C. Laura Sayas,Monica Mendes Sousa,Jesus Avila, published by Frontiers Media SA which was released on 2020-03-25. Get Shaping the Brain by Neuronal Cytoskeleton from Development to Disease and Regeneration

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Planar Cell Polarity During Development

This new volume of Current Topics in Developmental Biology covers the area of Planar Cell Polarity with contributions from an international board of authors. The 12 chapters provide a comprehensive set of reviews covering such topics as PCP in Zebra fish, the role of Dishevelled in PCP regulation, and PCP in

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