cell based liver regeneration

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Innovative Medicine
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Publisher : Springer
Release Date :
ISBN 10 : 4431556516
Pages : 339 pages
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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Innovative Medicine

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development

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Stem cell based liver regeneration

Download or read online Stem cell based liver regeneration written by Klaus Eckert,Max-Delbrück-Centrum für Molekulare Medizin, published by Unknown which was released on 2009. Get Stem cell based liver regeneration Books now! Available in PDF, ePub and Kindle.

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Cell Based Liver Regeneration

Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical

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Stem Cell and Liver Regeneration

Cellular therapy with liver stem cells and their progeny, including bone marrow cells, is a promising new approach that will contribute significantly to the treatment of liver diseases. The existence of the liver stem cell had long been debated, but it is now generally accepted that the liver contains cells

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Cell Based Liver Regeneration

Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical

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Regenerative Medicine  Stem Cells and the Liver

The regenerative capacity of the liver has been recognized for centuries, but when it is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells

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Hepatocyte Transplantation

In recent years there has been an increasing need for transplantation, but the number of donor livers available has increased only slightly, despite intensive public relations activities. New concepts in the field of transplantation, for instance the transplantation of living donor organs or the splitting of organs, are urgently required,

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Liver Regeneration and Carcinogenesis

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation

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Cardiac Regeneration

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and

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Bioengineering Liver Transplantation

The aim of this Special Issue is to review, understand, and evaluate new and exciting opportunities from the field on regenerative medicine, biomaterials, and stem cell research for the bioengineering of human liver grafts that can be applied for transplantation and personalized treatment of end-stage liver disease.The development of

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Liver Regeneration

Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in

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Liver Stem Cells

Increasing evidence suggests that liver stem cells have the capacity to differentiate into parenchymal hepatocytes or into bile ductular cells. These stem cells may be activated to proliferate after severe liver injury or exposure to hepatocarcinogens. Stem cell replacement strategies are being investigated as an alternative approach to liver repair

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High throughput Approaches to Sourcing of Human Hepatocytes for Cell based Therapies

Chronic liver disease affects more than 500 million people worldwide. The only therapy shown to directly prevent mortality is organ transplantation. However, there is growing discrepancy between supply and demand of transplant-grade organs and transplant recipients are subject to a lifetime of immunosuppressive regimens. Therefore, the overall aim of this thesis

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Stem Cells     From Hype to Real Hope

This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting

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Frontiers in Stem Cell and Regenerative Medicine Research

Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing

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