brain tumors

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Brain Tumors
Author :
Publisher : Springer Science & Business Media
Release Date :
ISBN 10 : 1592598439
Pages : 393 pages
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Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors is quite complex and the resulting tumors are characterized by a high degree of biological and clinical diversity. Thus, despite the advances of the last two decades, prognosis for patients with malignant brain tumors remains abysmal. Significant progress in the diagnosis, treatment and, ultimately, prevention of these tumors will require both the timely h- nessing of the advances in basic and clinical brain tumor research, and a continuing concerted effort at increasing our understanding of brain tumor biology, in particular, the molecular genetic changes and perturbations of cellular pathways involved in brain oncogenesis and which drive the biological and clinical behavior of the tumors. Brain tumor diagnosis and prognosis, which is still largely based on histopathology and other clinical criteria, will, in the future, acquire a significant molecular component, with the incorporation of knowledge of genes that are mutated, over-expressed, deleted, silenced, or functionally altered in the tumors. Treatment strategies for brain tumors, rather than being empirical, will be rationally developed based on an understanding of the cellular and molecular mechanisms and targets that have been activated, suppressed, or otherwise altered.

Brain Tumors

Exciting new developments and discoveries of the last two decades are beginning to shed light on the complex biology of brain tumors and are advancing our understa- ing of the cellular and molecular processes involved in their initiation, progression, and clinical and biological behavior. The disease process in brain tumors

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Brain Tumors

The third American edition has been completely revised and expanded, although parts of the text of the second edition have been included. I wish to acknowledge once again the excellent translation of the former two editions by Dr. ALAN B. ROTHBALLER and the late Dr. JERZY OLSZEWSKI. With this edition

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Brain Tumors

This text aims to provide a complete coverage of brain tumours, including their biological basis, diagnosis and management techniques. It describes the present concepts of the treatment of all brain tumours.

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Epilepsy and Brain Tumors

Patients with brain tumor-related epilepsy (BTRE) suffer from two serious pathologies simultaneously – a brain tumor and a secondary form of epilepsy. Although there has been remarkable progress in BTRE research in recent years, it remains an on-going challenge for clinicians and continues to stimulate much debate in the scientific community.

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Brain and Spinal Tumors of Childhood

This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through

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Brain Tumors

Analogue to the first edition, the principal characteristic of this work is its casting of pathology as the common nosographic link in the diagnosis, prognosis and treatment of brain tumours. A result of the author's many years of experience in the study of brain tumours and their pathological and clinical

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Innovative Brain Tumor Therapy

Despite recent advances, therapeutic efforts have not been successful establishing a definitive strategy of treatment for brain gliomas, because of the presence of the blood-brain barrier. Innovative Brain Tumor Therapy presents a synopsis of the studies on nanoparticles as ideal devices for brain tumor treatment. Their nanometric size, electrostatic charge,

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Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently,

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Handbook of Brain Tumor Chemotherapy

Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents.

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Brain Tumors

Written for neurologists and other physicians who participate in the diagnosis and treatment of brain tumors, this book synthesizes the authors' clinical experiences. The first seven chapters provide a foundation for tumor pathology, biology, radiology, and the treatment modalities of surgery, radiation therapy, and chemotherapy. The remaining eight chapters have

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Atlas of Brain Tumors

Despite recent technological innovations in neuroradiology, the ultimate diagnosis of brain tumors is still based on the histopathological findings from specimens taken during surgery. The material in this atlas represents approximately 700 brain tumor specimens collected mainly in the authors' own clinics. In most cases, complementary light-and-electron-microscopic images of the same

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100 Questions   Answers About Brain Tumors

Whether you’re a newly diagnosed brain tumor patient, a survivor, or a friend or relative of either, this book offers help. Completely revised and updated, 100 Questions & Answers About Brain Tumors, Second Edition gives you authoritative, practical answers to your questions about treatment options, post-treatment quality of life, sources of

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Fast Facts  Brain Tumors

Despite the availability of many effective treatments, there remains a therapeutic nihilism associated with brain tumors. This highly readable second edition of 'Fast Facts: Brain Tumors' challenges this view, starting from the premise that patients with brain tumors can truly benefit from a thoughtful multidisciplinary approach. This comprehensive handbook covers

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Therapeutic Ribonucleic Acids in Brain Tumors

In the past few years nucleic acids technologies have grown into a powerful analytical and also increasingly therapeutic tool. It has been applied not only to the uncovering of gene functions in many organisms, but also to pathogenetic analysis and recently also for the treatment of human diseases. The book

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Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors

Comprehensive Overview of Modern Surgical Approaches to Intrinsic Brain Tumors addresses limitations in the scientific literature by focusing primarily on surgical approaches to various intrinsic neoplasms using diagrams and step-by-step instructions. It provides the advantages and disadvantages of these approaches, controversies, and technical considerations and discusses topics such as anatomy,

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