biotextiles as medical implants

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Biotextiles as Medical Implants
Author :
Publisher : Elsevier
Release Date :
ISBN 10 : 0857095609
Pages : 704 pages
Rating : /5 ( users)
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Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first part of the book focuses on polymers, fibers and textile technologies, and these chapters discuss the manufacture, sterilization, properties and types of biotextiles used for medical applications, including nanofibers, resorbable polymers and shaped biotextiles. The chapters in part two provide a comprehensive discussion of a range of different clinical applications of biotextiles, including surgical sutures, arterial prostheses, stent grafts, percutaneous heart valves and drug delivery systems. This book provides a concise review of the technologies, properties and types of biotextiles used as medical devices. In addition, it addresses the biological dimension of how to design devices for different clinical applications, providing an invaluable reference for biomedical engineers of medical textiles, quality control and risk assessment specialists, as well as managers of regulatory affairs. The subject matter will also be of interest to professionals within the healthcare system including surgeons, nurses, therapists, sourcing and purchasing agents, researchers and students in different disciplines. Provides an invaluable single source of information on the main types of textile materials and products used for medical implants Addresses the technologies used and discusses the manufacture, properties and types of biotextiles Examines applications of biotextiles as medical implants, including drug delivery systems and stent grafts and percutaneous heart valves

Biotextiles as Medical Implants

Textiles play a vital role in the manufacture of various medical devices, including the replacement of diseased, injured or non-functioning organs within the body. Biotextiles as medical implants provides an invaluable single source of information on the main types of textile materials and products used for medical implants. The first

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Biotextiles as medical implants

Catgut and collagen are the two most well-known natural materials for absorbable sutures; however collagen-based absorbable sutures have largely been replaced by synthetic materials made from one of five basic building blocks. The chemical structures of a variety of commercial absorbable sutures are reviewed. The characteristics, chemistry and manufacture of

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Biotextiles as medical implants

The chapter describes the regulatory framework applicable to medical devices, and specifically to biotextiles, principally in the United States, but also in the European Union. With the emergence of new technologies and materials, new forms of regulation have become necessary, and some of the traditional classifications no longer match present-day

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Biotextiles as medical implants

The available implants can be classified as either the one- dimensional, two-dimensional or three-dimensional structures. Among these, the most researched is the arterial prosthesis, which involves a novel process and many steps to make. All aspects of the manufacture and finishing of different types of vascular grafts (straight, tapered, multilimbed)

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Biotextiles as medical implants

Biotextile sterilization presents unique challenges. The chapter describes the principles of sterilization and the way in which sterility assurance levels are defined and demonstrated. Traditional thermal, chemical and radiation sterilization methods are described, as well as newer methods such as plasma and microwave sterilization, and applications for which each is

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Biotextiles as medical implants

Three-dimensional nanofiber structures are desirable as scaffolds for tissue development since they mimic the natural environment of the cells. Various techniques have evolved to fabricate such structures using desired materials. Among these, electrospinning provides an advantage due to the ease of use and better control of the resulting structure. A

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Biotextiles as medical implants

Textiles are known to have unique properties that lend themselves to use in many different types of technical products, among which perhaps the best known are medical materials. Presented in this chapter are aspects of polymer, fiber and textile science that should serve as useful background knowledge of the materials

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Biotextiles as medical implants

Surface properties are a critical aspect of textiles for medical applications. This chapter discusses some popular surface modification techniques: plasma activation, plasma polymerization, chemical grafting, and polymer encapsulation of nanoparticles.

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Biotextiles as medical implants

The chapter describes properties of materials used for sutures that may be: absorbable or nonabsorbable; of varying size; made from monofilament, multifilament, twisted or braided threads. The characteristics of a large number of synthetic suture materials are described, together with essential suture properties such as tensile strength, knot strength, elasticity,

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Biotextiles as medical implants

The chapter discusses the characteristics of resorbable polymers used for medical applications, in particular in cardiovascular systems, in terms of their biocompatibility, resorbability, mechanical and degradation properties, manufacturing feasibility, sterilizability and shelf life. Polymers currently in use for biotextile applications are surveyed, together with recent advances in mechano-active engineering of

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Biotextiles as medical implants

The chapter discusses the advantages and limitations of arterial prostheses (or vascular grafts) in terms of their biocompatibility, biofunctionality and biostability. Criteria for biomaterials selection and prosthesis design that have enabled patients to recover more rapidly without any device-related complications are reviewed, and developments are considered that may lead to

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Biotextiles as medical implants

Developing novel drug delivery systems (DDSs) from drugloaded fibers is a useful and attractive medical applications of biotextiles. This chapter reviews relevant textile technologies, types of polymers and active pharmaceutical ingredients for preparing drug-loaded fibers. Different types of DDS derived from novel drug-loaded fibers are summarized. Future trends and areas

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Biotextiles as medical implants

This review summarizes barbed suture technology. It discusses their development, materials used, design and manufacture, testing and properties as well as applications.

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Biotextiles as medical implants

The chapter describes procedures and materials used and results obtained from several important studies of the mechanical performance of surgical sutures and the clinical factors that influence their behavior. Key features of successful suture assembly are the material used, structure of the thread, surface treatment, knot strength, and security, the

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Biotextiles as medical implants

Arterial grafts first appeared in the early 1950s, since when they have attracted much attention and undergone significant changes in structure and treatment. Arterial prostheses are now routinely used to correct arterial flow disorders. The success of large-diameter synthetic arteries has not been experienced in with small-caliber vessels. A major

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