antimalarial agents

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Antimalarial Agents
Author :
Publisher : Elsevier
Release Date :
ISBN 10 : 0081012101
Pages : 622 pages
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Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs. Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Antimalarial Agents

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have

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Antimalarial Agents

Medicinal Chemistry, Volume 12: Antimalarial Agents: Chemistry and Pharmacology presents the essentials of both biology and chemistry pertinent to the chemotherapy of malaria. This book discusses the nature of the disease, the physiology and biochemistry of the plasmodia, and the mode of action of drugs. Organized into 19 chapters, this volume begins

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Hepatotoxicity

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of

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Survey of Antimalarial Agents

Download or read online Survey of Antimalarial Agents written by George Robert Coatney, published by Unknown which was released on 1953. Get Survey of Antimalarial Agents Books now! Available in PDF, ePub and Kindle.

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Saving Lives  Buying Time

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising

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STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS

Download or read online STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS written by DOUGLAS CLIFFORD MORRISON, published by Unknown which was released on 1964. Get STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS Books now! Available in PDF, ePub and Kindle.

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Antimalarial Chemotherapy

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial

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Exam Prep for  Antimalarial Agents  Chemistry And

Download or read online Exam Prep for Antimalarial Agents Chemistry And written by Anonim, published by Unknown which was released on . Get Exam Prep for Antimalarial Agents Chemistry And Books now! Available in PDF, ePub and Kindle.

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An Overview of Tropical Diseases

Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such

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Guidelines for the Treatment of Malaria

Malaria is an important cause of death and illness in children and adults in tropical countries, and the mortality rate (which is currently estimated at over a million people per year) has risen in recent years, probably due to increasing resistance to antimalarial medicines. Malaria control requires an integrated approach

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From Artemisia Annua L  to Artemisinins  Hindi Edition

From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief

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Antimalarial Agents  An Update on Synthetic Variants of Chloroquine

Download or read online Antimalarial Agents An Update on Synthetic Variants of Chloroquine written by Anupama Parate, published by Unknown which was released on 2019. Get Antimalarial Agents An Update on Synthetic Variants of Chloroquine Books now! Available in PDF, ePub and Kindle.

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Tandem Mass Spectrometry

Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem

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Malaria

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations

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Artemisia

A comprehensive overview of this genus, Artemisia examines all aspects of the herbs uses and applications, its mode of action and clinical importance. Following a comprehensive introduction to the genus, the book discusses the botanical, phytochemical and biological aspects of a number of important species of Artemisis. Considering that the

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