100 years of human chorionic gonadotropin

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100 Years of Human Chorionic Gonadotropin
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Publisher : Unknown
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ISBN 10 : 0128200502
Pages : 358 pages
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100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

100 Years of Human Chorionic Gonadotropin

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions

GET BOOK!
100 Years of Human Chorionic Gonadotropin

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of

GET BOOK!
Human Chorionic Gonadotropin  hCG

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of

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Human Chorionic Gonadotropin  hCG

This resource describes the detailed biology, clinical chemistry, and clinical perspectives of HCG and associated molecules and examines HCG, hyperglycosylated HCG, and HCG free-subunit, three separate and independent molecules with totally sovereign physiological functions.

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Chorionic Gonadotropin

This volume is devoted to the chemistry, immunology, molecular biology, and physiology of the human chorionic gonadotropin, heG. For this glycoprotein molecule the course from discovery to chemical deciphering covered about fifty years. It was in 1928 that Ascheim and Zondek reported that urine from pregnant women contains something that stimulates

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Human Chorionic Gonadotropin and Gonadotropin releasing Hormone Influence Pregnancy Survival and Resynchronized Ovulation Before Timed Artificial Insemination in Holstein Cattle

A study was performed to determine the minimum effective dose of human chorionic gonadotropin (hCG) needed to induce ovulation of follicles in cattle (Exp. 1). Another study determined the effects of replacing the first injection of GnRH (d -7) with hCG or saline in a Resynch-Ovsynch protocol [injection of GnRH 7 d

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100 Years of Research

Download or read online 100 Years of Research written by Anonim, published by Unknown which was released on 1983. Get 100 Years of Research Books now! Available in PDF, ePub and Kindle.

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One Hundred Years of Pharmacology  1891 1991

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Principles of Neurological Surgery E Book

Principles of Neurosurgery, by Drs. Richard G. Ellenbogen, Saleem I. Abdulrauf and Laligam N Sekhar, provides a broad overview of neurosurgery ideal for anyone considering or training in this specialty. From general principles to specific techniques, it equips you with the perspectives and skills you need to succeed. Comprehensive without

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Marine Fish Culture

4 Water Sources ........................................ 149 Criteria ............................................. 149 Major types .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 . . . . . . . . . . . . Summary ............................................ 152 5 Water Treatment ...................................... 155 Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 . . . . . . . . . . . . Materials ............................................ 155 Treatment options . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 . . . . . . . . . . . System design ........................................ 169 System monitoring and control . . . . . . . . . . . . . . . . . . . . . 172 . . . . . . . . Environmental considerations .............................. 174 Summary ............................................ 174 6 Culture Units ......................................... 175 Considerations in choosing culture units ...................... 175 Characteristics of culture units . . . . . . . . . . . . . . . . . . . . . 175 . . . . . . . . Applications of culture units .............................. 191 Hatchery design " . . . . . . . . . . . . . . . . . . . . . . . . . . 208 . . . . . . . . . . . Summary ............................................ 210 7 Obtaining Fish for Stocking . ............................. 211 Stock from the wild .................................... 211 Stock from the

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Immunology of Pregnancy 2013

Since a September, 1992, Nature article which read: “Can there be life without LIF?”, researchers now realize that the maternal immune system is both a foe (it can reject the conception) and a friend (immune cells and molecules are also necessary for successful pregnancy). Leukemia Inhibitory Factor (LIF) when absent, prevents

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Williams Textbook of Endocrinology

For more than 65 years, Williams Textbook of Endocrinology has been the gold standard in the field, delivering authoritative guidance on every aspect of adult and pediatric endocrine system disorders. The 13th Edition has been thoroughly updated by Drs. Shlomo Melmed, Kenneth S. Polonsky, P. Reed Larsen, and Henry M. Kronenberg,

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Advances in Cancer Biomarkers

At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view,

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